the science

Peptides are small chains of amino acids that act as signaling molecules in the body, facilitating communication between cells and triggering specific biological responses. The peptides in Kambo are unique to the Giant Monkey Tree Frog (Phyllomedusa bicolor) and have been recognized for their ability to bind to human cell receptors with remarkable precision, creating a wide range of physiological effects.

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• Phyllocaerulein

  • Role: A powerful natural analgesic and opiate-like peptide.

  • Effects: Reduces pain, lowers blood pressure, improves digestion, and increases blood circulation. It also induces a calming and relaxing effect, making it particularly beneficial for stress-related conditions.

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• Phyllokinin

  • Role: A potent vasodilator.

  • Effects: Improves blood flow by widening blood vessels, supports better oxygen delivery to tissues, and has anti-inflammatory properties. It may also help reduce blood pressure.

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• Dermorphin

  • Role: An opioid peptide.

  • Effects: Provides natural pain relief, significantly more potent than morphine, without the side effects of synthetic opioids. It enhances feelings of well-being and reduces physical discomfort.

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• Deltorphin

  • Role: Another potent opioid peptide.

  • Effects: Targets specific receptors in the brain to provide powerful pain relief and promote emotional balance. It is also known for its mood-enhancing properties.

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• Sauvagine

  • Role: A peptide that mimics the effects of corticotropin-releasing hormone.

  • Effects: Helps regulate stress responses by reducing anxiety, balancing cortisol levels, and improving mental clarity. It also supports the body's ability to handle emotional and physical stress.

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• Bombesins

  • Role: A group of peptides that influence the gastrointestinal and nervous systems.

  • Effects: Stimulate the release of digestive enzymes, regulate appetite, and support gut health. Bombesins also have antimicrobial properties, aiding in the body’s defense against harmful bacteria.

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• Caeruleins

  • Role: Similar to phyllocaerulein but with additional functions.

  • Effects: Stimulate smooth muscle contractions, aiding in digestion and detoxification. They also contribute to pain relief and anti-inflammatory effects.

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• Adenoregulin

  • Role: Interacts with the body’s adenosine receptors.

  • Effects: Enhances the body’s ability to utilize energy efficiently, improves cellular communication, and has potential anti-cancer properties by regulating cell growth.

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• Dermaseptins

  • Role: Antimicrobial peptides.

  • Effects: Fight a wide range of pathogens, including bacteria, fungi, and viruses. They support the immune system by providing a natural line of defense against infections.

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• Tryptophyllins

  • Role: Anti-inflammatory peptides.

  • Effects: Reduce inflammation, support tissue repair, and promote faster recovery from injuries. They also have potential anti-cancer properties due to their ability to inhibit tumor growth.

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• Bradykinins

  • Role: Peptides involved in blood pressure regulation.

  • Effects: Promote vasodilation, improve circulation, and have strong anti-inflammatory effects, which can alleviate conditions like arthritis or chronic pain.